TDP2 anticorps (Middle Region)

N° du produit ABIN2777707

Détail du produit anti-TDP2 anticorps

Antigène: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TDP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IPPYYSYLKK RSSNYEIITG HEEGYFTAIM LKKSRVKLKS QEIIPFPSTK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TTRAP. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TTRAP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 362 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TDP2 (ABIN2777707)

Xu, Pan, Wang, Huang, Tian, Xue, Chen, Jia: "TTRAP is a novel PML nuclear bodies-associated protein." dans: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 395-8, (2008) (PubMed).

Détails sur TDP2

Antigène: TDP2 (tyrosyl-DNA phosphodiesterase 2 (TDP2))

Autre désignation: TTRAP (TDP2 Produits)

Synonymes: anticorps AD022, anticorps EAP2, anticorps EAPII, anticorps TTRAP, anticorps dJ30M3.3, anticorps hTDP2, anticorps ad022, anticorps eap2, anticorps ttrap, anticorps D13Ertd656e, anticorps Ttrap, anticorps tdp2, anticorps ttrapl, anticorps tyrosyl-DNA phosphodiesterase 2, anticorps tyrosyl-DNA phosphodiesterase 2 S homeolog, anticorps tyrosyl-DNA phosphodiesterase 2b, anticorps TDP2, anticorps tdp2.S, anticorps Tdp2, anticorps tdp2b

Sujet: The TTRAP gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Alias Symbols: TDP2, EAP2, AD022, EAPII, TTRAP, dJ30M3.3, RP1-30M3.3
Protein Interaction Partner: UBC, SRPK2, SUMO1, SUMO2, SUMO3, TAP1, SKIL, ATXN1, PSEN1, SMAD3, EPS8, DLX3, ATP5G2, C2orf88, JAM2, SNX13, AKAP9, RAB11A, PARK7, MAPK6, UBE2I, TRAF5, TRAF6, TRAF3, TRAF2, FLI1, TNFRSF1B, ETS2, ETS1, TNFRSF8, CD40, HTNVsSgp1,
Protein Size: 362

Poids moléculaire: 41 kDa

ID gène: 51567

NCBI Accession: NM_016614, NP_057698

UniProt: O95551