PIAS4 anticorps (N-Term)

N° du produit ABIN2777708

Détail du produit anti-PIAS4 anticorps

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS4 est non-conjugé

Application: Western Blotting (WB)

Séquence: AKNMVMSFRV SDLQMLLGFV GRSKSGLKHE LVTRALQLVQ FDCSPELFKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Attributs du produit: This is a rabbit polyclonal antibody against PIAS4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PIAS4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 510 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PIAS4 (ABIN2777708)

Zhang, Xu, Han, Wei, Shu: "PIASy represses TRIF-induced ISRE and NF-kappaB activation but not apoptosis." dans: FEBS letters, Vol. 570, Issue 1-3, pp. 97-101, (2004) (PubMed).

Détails sur PIAS4

Antigène: PIAS4 (Protein Inhibitor of Activated STAT, 4 (PIAS4))

Autre désignation: PIAS4 (PIAS4 Produits)

Synonymes: anticorps PIASY, anticorps Piasg, anticorps ZMIZ6, anticorps pias4, anticorps piasy, anticorps wu:fc54c11, anticorps wu:fi18c10, anticorps wu:fi20e09, anticorps wu:fk93f11, anticorps zgc:66410, anticorps piasg, anticorps zmiz6, anticorps LOC100219439, anticorps Pias-gamma, anticorps pias4l, anticorps wu:fi26h11, anticorps zgc:63923, anticorps protein inhibitor of activated STAT 4, anticorps protein inhibitor of activated STAT, 4, anticorps protein inhibitor of activated STAT, 4a, anticorps protein inhibitor of activated STAT 4 L homeolog, anticorps protein inhibitor of activated STAT, 4b, anticorps PIAS4, anticorps Pias4, anticorps pias4a, anticorps pias4.L, anticorps pias4, anticorps pias4b

Sujet: PIAS4 is an inhibitor of TRIF-induced ISRE and NF-kappaB activation. Its mRNA is selectively expressed in endothelial cells, and its expression can be regulated by angiogenic growth factors
Alias Symbols: PIASY, Piasg, ZMIZ6
Protein Interaction Partner: HNF4A, HIC1, IKBKG, UBE2I, VHL, SUMO1, SUMO2, PDE4D, PDE4A, MECOM, UBC, SKIL, SERPINA5, OAZ1, SMAD7, SMAD1, LAMP2, KRT18, IRF7, IRF3, IL15RA, FTH1, ESRRA, TICAM1, ZNF512B, PHF11, PHGDH, MPRIP, HNRNPUL1, OPTN, PDE4DIP, PIAS2, BTAF1, ALDOA, ACTN1, PLAG1, Ga
Protein Size: 510

Poids moléculaire: 57 kDa

ID gène: 51588

NCBI Accession: NM_015897, NP_056981

UniProt: Q8N2W9

Pathways: Signalistation JAK/STAT, Interferon-gamma Pathway, Positive Regulation of Response to DNA Damage Stimulus