ARID4A anticorps (C-Term)
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- Antigène Voir toutes ARID4A Anticorps
- ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))
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Épitope
- C-Term
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Reactivité
- Humain, Chien, Boeuf (Vache), Souris, Porc, Lapin, Rat, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ARID4A est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- NSSKCTPVKH LNVSKPQKLA RSPARISPHI KDGEKDKHRE KHPNSSPRTY
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 93%
- Attributs du produit
- This is a rabbit polyclonal antibody against ARID4A. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A
- Top Product
- Discover our top product ARID4A Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1257 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 43, Issue 11, pp. 1211-23, (2014) (PubMed).
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Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development." dans: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 43, Issue 11, pp. 1211-23, (2014) (PubMed).
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- Antigène
- ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))
- Autre désignation
- ARID4A (ARID4A Produits)
- Synonymes
- anticorps wu:fc43f03, anticorps wu:fi06c05, anticorps wu:fi11g07, anticorps wu:fi14h03, anticorps zgc:110391, anticorps ARID4A, anticorps rbp1, anticorps rbbp1, anticorps rbp-1, anticorps MGC130902, anticorps RBBP-1, anticorps RBBP1, anticorps RBP-1, anticorps RBP1, anticorps A630009N03, anticorps A630067N03Rik, anticorps MmRBBP1, anticorps Rbbp1, anticorps AT rich interactive domain 4A (RBP1-like), anticorps AT-rich interaction domain 4A, anticorps AT-rich interaction domain 4A L homeolog, anticorps arid4a, anticorps ARID4A, anticorps arid4a.L, anticorps Arid4a
- Sujet
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ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
Alias Symbols: RBP1, RBBP1, RBP-1, RBBP-1
Protein Interaction Partner: SUMO2, SUMO1, HDAC1, BRMS1, HIST2H3C, HIST4H4, UBC, CDK2, CDK1, CCNE1, CCNB1, CCNA2, CCND1, CDK4, SIN3A, SAP30, RB1, SIN3B, RBBP7, RBBP4, ARID4B, HDAC3, EID1, HDAC2, ING2, RBL1,
Protein Size: 1257 - Poids moléculaire
- 143 kDa
- ID gène
- 5926
- NCBI Accession
- NM_002892, NP_002883
- UniProt
- P29374
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