RING1 anticorps (Middle Region)
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- Antigène Voir toutes RING1 Anticorps
- RING1 (Ring Finger Protein 1 (RING1))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp RING1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- APSPPEPGGE IELVFRPHPL LVEKGEYCQT RYVKTTGNAT VDHLSKYLAL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against RING1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human RING1
- Top Product
- Discover our top product RING1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 406 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- RING1 (Ring Finger Protein 1 (RING1))
- Autre désignation
- RING1 (RING1 Produits)
- Synonymes
- anticorps RING1A, anticorps RNF1, anticorps Ring1A, anticorps bap-1, anticorps bap1, anticorps ding, anticorps hipi3, anticorps ring1a, anticorps ring1b, anticorps ring2, anticorps rnf1, anticorps rnf2-a, anticorps ring1, anticorps ring1b-B, anticorps rnf2-b, anticorps ring finger protein 1, anticorps ring finger protein 1 S homeolog, anticorps ring finger protein 1 L homeolog, anticorps RING1, anticorps Ring1, anticorps ring1.S, anticorps ring1.L
- Sujet
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RING1 belongs to the RING finger family, members of which characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The protein can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. RING1 interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. This gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF1, RING1A
Protein Interaction Partner: CBX8, RYBP, YAF2, BMI1, UBC, SNAI1, EED, RNF2, HECW2, CSNK2A2, YY1, FBXO38, CBX7, CBX6, FHL1, TP53, NOTCH1, APP, PCGF1, PCGF5, PCGF6, PCGF3, PCGF2, CBX2, PHC3, WDR5, CBX4, PHC2, PHC1, YY2, ZFP42, SMARCAD1, PIK3R3, TOP2A, TERF2, TERF1, USP11, USP7, CENPA,
Protein Size: 406 - Poids moléculaire
- 42 kDa
- ID gène
- 6015
- NCBI Accession
- NM_002931, NP_002922
- UniProt
- Q06587
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