BCL11B anticorps (Middle Region)

N° du produit ABIN2777845

Détail du produit anti-BCL11B anticorps

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BCL11B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QASKLKRHMK THMHKAGSLA GRSDDGLSAA SSPEPGTSEL AGEGLKAADG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against BCL11B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human BCL11B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 823 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur BCL11B

Antigène: BCL11B (B-Cell CLL/lymphoma 11B (Zinc Finger Protein) (BCL11B))

Autre désignation: BCL11B (BCL11B Produits)

Synonymes: anticorps BCL11B, anticorps 9130430L19Rik, anticorps AI604821, anticorps B630002E05Rik, anticorps BCL-11B, anticorps Ctip2, anticorps Rit1, anticorps ATL1, anticorps ATL1-alpha, anticorps ATL1-beta, anticorps ATL1-delta, anticorps ATL1-gamma, anticorps CTIP-2, anticorps CTIP2, anticorps RIT1, anticorps ZNF856B, anticorps hRIT1-alpha, anticorps B-cell CLL/lymphoma 11B, anticorps B cell leukemia/lymphoma 11B, anticorps B-cell CLL/lymphoma 11B (zinc finger protein), anticorps BCL11B, anticorps Bcl11b

Sujet: BCL11B is the tumor-suppressor protein involved in T-cell lymphomas. BCL11B may function on the P53-signaling pathway. BCL11B may be a key regulator of both differentiation and survival during thymocyte development. BCL11B repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported.
Alias Symbols: CTIP-2, CTIP2, RIT1, hRIT1-alpha, ZNF856B
Protein Interaction Partner: HDAC6, HDAC2, HDAC1, NOTCH1, UBC, HDAC3, SUV39H1, tat, CBX5, NR2F1, SP1, MBD3, MTA2, MTA1, RBBP7, RBBP4, CHD4, NR2F2,
Protein Size: 823

Poids moléculaire: 88 kDa

ID gène: 64919

NCBI Accession: NM_022898, NP_075049