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MRPS15 anticorps (N-Term)

MRPS15 Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777848
  • Antigène Voir toutes MRPS15 Anticorps
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    Épitope
    • 7
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    Humain, Souris, Rat, Lapin, Boeuf (Vache), Cobaye, Cheval, Chien
    Hôte
    • 31
    • 2
    Lapin
    Clonalité
    • 31
    • 2
    Polyclonal
    Conjugué
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MRPS15 est non-conjugé
    Application
    • 25
    • 15
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    RGYVVRKPAQ SRLDDDPPPS TLLKDYQNVP GIEKVDDVVK RLLSLEMANK
    Homologie
    Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 83%, Rabbit: 86%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against MRPS15. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human MRPS15
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 257 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Davies, Rackham, Shearwood, Hamilton, Narsai, Whelan, Filipovska: "Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation." dans: FEBS letters, Vol. 583, Issue 12, pp. 1853-8, (2009) (PubMed).

  • Antigène
    MRPS15 (Mitochondrial Ribosomal Protein S15 (MRPS15))
    Autre désignation
    MRPS15 (MRPS15 Produits)
    Synonymes
    anticorps CG4207, anticorps DmMRPS15, anticorps Dmel\\CG4207, anticorps MRP-S15, anticorps mRpS15, anticorps zgc:92862, anticorps MPR-S15, anticorps RPMS15, anticorps S15mt, anticorps 1500003E24Rik, anticorps 2410002B11Rik, anticorps Mprs15, anticorps CG4207 gene product from transcript CG4207-RA, anticorps mitochondrial ribosomal protein S15, anticorps mitochondrial ribosomal protein S15 L homeolog, anticorps bonsai, anticorps mrps15, anticorps MRPS15, anticorps mrpS15, anticorps mrps15.L, anticorps Mrps15
    Sujet
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. MRPS15 is a 28S subunit protein that belongs to the ribosomal protein S15P family.Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S15P family. The encoded protein is more than two times the size of its E. coli counterpart, with the 12S rRNA binding sites conserved. Between human and mouse, the encoded protein is the least conserved among small subunit ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 15q and 19q.
    Alias Symbols: DC37, FLJ11564, MPR-S15, RPMS15, S15mt
    Protein Interaction Partner: GRSF1, UBC, PARK2, ESR2, PTCD3, CAND1, COPS5, CUL3, SUMO2, ICT1,
    Protein Size: 257
    Poids moléculaire
    30 kDa
    ID gène
    64960
    NCBI Accession
    NM_031280, NP_112570
    UniProt
    P82914
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