SLUG anticorps (Middle Region)
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- Antigène Voir toutes SLUG (SNAI2) Anticorps
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Mouton, Chien, Cheval, Lapin, Cobaye, Saccharomyces cerevisiae
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SLUG est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- SDTSSKDHSG SESPISDEEE RLQSKLSDPH AIEAEKFQCN LCNKTYSTFS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%
- Attributs du produit
- This is a rabbit polyclonal antibody against SNAI2. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SNAI2
- Top Product
- Discover our top product SNAI2 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 268 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
- Autre désignation
- SNAI2 (SNAI2 Produits)
- Sujet
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SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10182, SLUG, SLUGH1, WS2D, SNAIL2
Protein Interaction Partner: SAT1, TRIM23, PPP2R2D, PPP6R3, STUB1, TJP2, UBC, TP53, PSMD3, PSMD1, PSMC1, PSMA3, PPP2CB, GSK3B, MDM2, APP, KDM1A, HDAC1, CHD4, Sin3a, HDAC2,
Protein Size: 268 - Poids moléculaire
- 30 kDa
- ID gène
- 6591
- NCBI Accession
- NM_003068, NP_003059
- UniProt
- O43623
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