EPC1 anticorps (Middle Region)

N° du produit ABIN2777875

Détail du produit anti-EPC1 anticorps

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Épitope: Middle Region

Reactivité: Humain, Souris, Lapin, Boeuf (Vache), Rat, Chien, Cheval, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EPC1 est non-conjugé

Application: Western Blotting (WB)

Séquence: VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human EPC1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 836 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur EPC1

Antigène: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Autre désignation: EPC1 (EPC1 Produits)

Synonymes: anticorps EPC1, anticorps Epl1, anticorps 2400007E14Rik, anticorps 5730566F07Rik, anticorps A930032N02Rik, anticorps epc1, anticorps enhancer of polycomb homolog 1, anticorps enhancer of polycomb homolog 1 (Drosophila) a, anticorps enhancer of polycomb homolog 1 (Drosophila), anticorps enhancer of polycomb homolog 1 L homeolog, anticorps EPC1, anticorps epc1a, anticorps Epc1, anticorps epc1, anticorps epc1.L

Sujet: EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Alias Symbols: DKFZp781P2312, Epl1
Protein Interaction Partner: RINT1, KRT15, Hopx, TRIM27, H2AFZ, DMAP1, ING3, MORF4L1, KAT5, MYC, MORF4L2, MRGBP, EED, EZH2, E2F6, SRF,
Protein Size: 836

Poids moléculaire: 93 kDa

ID gène: 80314

NCBI Accession: NM_025209, NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation