TBX3 anticorps (Middle Region)

N° du produit ABIN2777925

Détail du produit anti-TBX3 anticorps

Antigène: TBX3 (T-Box 3 (TBX3))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TBX3 est non-conjugé

Application: Western Blotting (WB)

Séquence: CRDKGSPAVK AHLFAAERPR DSGRLDKASP DSRHSPATIS SSTRGLGAEE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TBX3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 600 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TBX3 (ABIN2777925)

Bozyk, Popova, Bentley, Goldsmith, Linn, Weiss, Hershenson: "Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression." dans: Stem cells and development, Vol. 20, Issue 11, pp. 1995-2007, (2011) (PubMed).

Yano, Yamazaki, Adachi, Okawa, Fort, Uji, Tsukita, Tsukita: "Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling." dans: The Journal of cell biology, Vol. 193, Issue 2, pp. 319-32, (2011) (PubMed).

Détails sur TBX3

Antigène: TBX3 (T-Box 3 (TBX3))

Autre désignation: TBX3 (TBX3 Produits)

Synonymes: anticorps xtbx3, anticorps ums, anticorps xhl, anticorps tbx3-iso, anticorps TBX3, anticorps TBX3-ISO, anticorps UMS, anticorps XHL, anticorps D5Ertd189e, anticorps T-box 3, anticorps T-box 3 S homeolog, anticorps TBX3, anticorps tbx3.S, anticorps tbx3, anticorps Tbx3

Sujet: TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
Alias Symbols: UMS, XHL, TBX3-ISO
Protein Interaction Partner: CA8, AES, SOX2, Dlg4, ELAVL1, HDAC5, HDAC3, HDAC2, HDAC1, TOLLIP, TBX3,
Protein Size: 600

Poids moléculaire: 66 kDa

ID gène: 6926

Pathways: Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development