TEAD4 anticorps (Middle Region)

N° du produit ABIN2777935

Détail du produit anti-TEAD4 anticorps

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Cobaye, Cheval, Lapin, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEAD4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Séquence: LVKFWADLNT NIEDEGSSFY GVSSQYESPE NMIITCSTKV CSFGKQVVEK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 77%

Attributs du produit: This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human TEAD4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 391 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-TEAD4 (ABIN2777935)

Chan, Lim, Loo, Chong, Huang, Hong: "TEADs mediate nuclear retention of TAZ to promote oncogenic transformation." dans: The Journal of biological chemistry, Vol. 284, Issue 21, pp. 14347-58, (2009) (PubMed).

Détails sur TEAD4

Antigène: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Autre désignation: TEAD4 (TEAD4 Produits)

Synonymes: anticorps TEAD4, anticorps rtef1, anticorps tef-3, anticorps eftr-2, anticorps tefr-1, anticorps tcf13l1, anticorps hrtef-1b, anticorps xdtef-1, anticorps xlDTEF-1, anticorps RTEF-1, anticorps TEF-1, anticorps TEF-3, anticorps EFTR-2, anticorps RTEF1, anticorps TCF13L1, anticorps TEF3, anticorps TEFR-1, anticorps hRTEF-1B, anticorps ETFR-2, anticorps Etfr2, anticorps FR-19, anticorps TEAD-4, anticorps Tcf13r1, anticorps Tef3, anticorps Tefr, anticorps Tefr1, anticorps Tefr1a, anticorps TEA domain transcription factor 4, anticorps TEA domain transcription factor 4 S homeolog, anticorps TEA domain family member 4, anticorps TEAD4, anticorps tead4, anticorps tead4.S, anticorps Tead4

Sujet: TEAD4 is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this protein.This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.
Alias Symbols: EFTR-2, MGC9014, RTEF1, TCF13L1, TEF-3, TEFR-1, hRTEF-1B, TEF3
Protein Interaction Partner: CCDC172, SSX2IP, LZTS2, CEP70, CEP55, RABGEF1, CCNDBP1, KIAA0753, PNMA1, TRAF1, VPS52, TRIM27, GOLGA2, UBC, SUMO2, CCDC85B, WWTR1, YAP1, VGLL1, MYH7,
Protein Size: 391

Poids moléculaire: 44 kDa

ID gène: 7004

NCBI Accession: NM_201441, NP_958849

UniProt: Q15561

Pathways: Regulation of Lipid Metabolism by PPARalpha