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TUB anticorps (N-Term)

TUB Reactivité: Humain, Souris, Rat, Cheval, Lapin, Chien, Cobaye WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2777955
  • Antigène Voir toutes TUB Anticorps
    TUB (Tubby Homolog (TUB))
    Épitope
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 10
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Cheval, Lapin, Chien, Cobaye
    Hôte
    • 11
    • 1
    Lapin
    Clonalité
    • 12
    Polyclonal
    Conjugué
    • 12
    Cet anticorp TUB est non-conjugé
    Application
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA
    Homologie
    Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%
    Attributs du produit
    This is a rabbit polyclonal antibody against TUB. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human TUB
    Top Product
    Discover our top product TUB Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 561 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    TUB (Tubby Homolog (TUB))
    Autre désignation
    TUB (TUB Produits)
    Synonymes
    anticorps rd5, anticorps tubby, anticorps MGC79522, anticorps TUB, anticorps MGC80126, anticorps MGC84061, anticorps tub, anticorps tubby bipartite transcription factor, anticorps tubby bipartite transcription factor S homeolog, anticorps tub, anticorps TUB, anticorps tub.S, anticorps Tub
    Sujet
    TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
    Alias Symbols: rd5
    Protein Interaction Partner: UBC, SUV420H2, GNAQ, SRC, ABL1, PLCG1, PIK3R1, LCK, JAK2, IRS1, GRB2,
    Protein Size: 561
    Poids moléculaire
    62 kDa
    ID gène
    7275
    NCBI Accession
    NM_003320, NP_003311
    UniProt
    P50607
    Pathways
    Signalisation RTK, Sensory Perception of Sound
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