TUB anticorps (N-Term)

N° du produit ABIN2777955

Détail du produit anti-TUB anticorps

Antigène: TUB (Tubby Homolog (TUB))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Lapin, Chien, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: DSLASVQLGA TRPTAPASAK RTKAAATAGG QGGAARKEKK GKHKGTSGPA

Homologie: Dog: 92%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against TUB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human TUB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 561 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TUB

Antigène: TUB (Tubby Homolog (TUB))

Autre désignation: TUB (TUB Produits)

Synonymes: anticorps rd5, anticorps tubby, anticorps MGC79522, anticorps TUB, anticorps MGC80126, anticorps MGC84061, anticorps tub, anticorps tubby bipartite transcription factor, anticorps tubby bipartite transcription factor S homeolog, anticorps tub, anticorps TUB, anticorps tub.S, anticorps Tub

Sujet: TUB functions in signal transduction from heterotrimeric G protein-coupled receptors. It could be involved in the hypothalamic regulation of body weight. This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: rd5
Protein Interaction Partner: UBC, SUV420H2, GNAQ, SRC, ABL1, PLCG1, PIK3R1, LCK, JAK2, IRS1, GRB2,
Protein Size: 561

Poids moléculaire: 62 kDa

ID gène: 7275

NCBI Accession: NM_003320, NP_003311

UniProt: P50607

Pathways: Signalisation RTK, Sensory Perception of Sound