Claudin 1 anticorps (C-Term)

N° du produit ABIN2778045

Détail du produit anti-Claudin 1 anticorps

Antigène: Claudin 1 (CLDN1)

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Mouton, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GQALFTGWAA ASLCLLGGAL LCCSCPRKTT SYPTPRPYPK PAPSSGKDYV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CLDN1. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 211 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Claudin 1 (ABIN2778045)

Coyne, Gambling, Boucher, Carson, Johnson: "Role of claudin interactions in airway tight junctional permeability." dans: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 5, pp. L1166-78, (2003) (PubMed).

Détails sur Claudin 1

Antigène: Claudin 1 (CLDN1)

Autre désignation: CLDN1 (CLDN1 Produits)

Synonymes: anticorps CLD1, anticorps ILVASC, anticorps SEMP1, anticorps AI596271, anticorps cldn19, anticorps claudin-1, anticorps cld1, anticorps ilvasc, anticorps semp1, anticorps CLDN1, anticorps claudin 1, anticorps claudin 1 S homeolog, anticorps CLDN1, anticorps Cldn1, anticorps cldn1, anticorps cldn1.S

Sujet: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
Alias Symbols: CLD1, SEMP1, ILVASC
Protein Interaction Partner: UBC, DRG1, LNX1, TJP3, BRD4, MPDZ, TJP2, CLDN1, INADL, CLDN3, WNK4, TJP1, MMP14, MMP2, CLDN5,
Protein Size: 211

Poids moléculaire: 23 kDa

ID gène: 9076

NCBI Accession: NM_021101, NP_066924

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C