Claudin 5 anticorps (C-Term)

N° du produit ABIN2778047

Détail du produit anti-Claudin 5 anticorps

Antigène: Claudin 5 (CLDN5)

Épitope: C-Term

Reactivité: Humain, Rat, Souris, Porc, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Claudin 5 est non-conjugé

Application: Western Blotting (WB)

Séquence: GWAATALLMV GGCLLCCGAW VCTGRPDLSF PVKYSAPRRP TATGDYDKKN

Homologie: Cow: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against CLDN5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN5

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 218 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Claudin 5 (ABIN2778047)

Yang, Liu, Miao, Yang, Fu, Dou, Cai, Zong, Tan, Chen, Wang: "Induction of VEGFA and Snail-1 by meningitic Escherichia coli mediates disruption of the blood-brain barrier." dans: Oncotarget, Vol. 7, Issue 39, pp. 63839-63855, (2016) (PubMed).

Fontijn, Volger, Fledderus, Reijerkerk, de Vries, Horrevoets: "SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function." dans: American journal of physiology. Heart and circulatory physiology, Vol. 294, Issue 2, pp. H891-900, (2008) (PubMed).

Détails sur Claudin 5

Antigène: Claudin 5 (CLDN5)

Autre désignation: CLDN5 (CLDN5 Produits)

Synonymes: anticorps AWAL, anticorps BEC1, anticorps CPETRL1, anticorps TMVCF, anticorps cld5, anticorps awal, anticorps bec1, anticorps claudin-5, anticorps cpetrl1, anticorps tmvcf, anticorps AI854493, anticorps MBEC1, anticorps Tmvcf, anticorps cldn5, anticorps zgc:85723, anticorps zgc:103419, anticorps claudin 5, anticorps Claudin-5, anticorps claudin 5 (transmembrane protein deleted in velocardiofacial syndrome), anticorps claudin 5a, anticorps claudin 5b, anticorps claudin 5 (transmembrane protein deleted in velocardiofacial syndrome) L homeolog, anticorps CLDN5, anticorps cld5, anticorps cldn5, anticorps Cldn5, anticorps cldn5a, anticorps cldn5b, anticorps cldn5.L

Sujet: CLDN5 is a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome.This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AWAL, BEC1, CPETRL1, TMVCF
Protein Interaction Partner: UBC, MPDZ, CLDN3, CLDN5, TJP1, CLDN1,
Protein Size: 218

Poids moléculaire: 23 kDa

ID gène: 7122

NCBI Accession: NM_003277, NP_003268

UniProt: O00501

Pathways: Hepatitis C