Claudin 11 anticorps (C-Term)
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- Antigène Voir toutes Claudin 11 (CLDN11) Anticorps
- Claudin 11 (CLDN11)
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Épitope
- C-Term
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Chien, Lapin, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Claudin 11 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- VSFGYSLYAG WIGAVLCLVG GCVILCCAGD AQAFGENRFY YTAGSSSPTH
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against CLDN11. It was validated on Western Blot and immunohistochemistry.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN11
- Top Product
- Discover our top product CLDN11 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 207 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Claudin 11 (CLDN11)
- Autre désignation
- CLDN11 (CLDN11 Produits)
- Synonymes
- anticorps cldn11, anticorps fb97c11, anticorps wu:fb97c11, anticorps claudin-11, anticorps CLDN11, anticorps Claudin-11, anticorps DKFZp459H2322, anticorps OSP, anticorps OTM, anticorps Claudin11, anticorps Osp, anticorps Otm, anticorps claudin 11b, anticorps claudin 11, anticorps cldn11b, anticorps CLDN11, anticorps Cldn11
- Sujet
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CLDN11 belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.The protein encoded by this gene belongs to the claudin family of tight junction associated proteins and is a major component of central nervous system myelin that is necessary for normal CNS function. There is growing evidence that the protein determines the permeability between layers of myelin sheaths via focal adhesion and, with its expression highly regulated during development, may play an important role in cellular proliferation and migration. In addition, the protein is a candidate autoantigen in the development of autoimmune demyelinating disease.
Alias Symbols: OSP, OTM
Protein Interaction Partner: UBC, TSPAN3, TSPAN4,
Protein Size: 207 - Poids moléculaire
- 22 kDa
- ID gène
- 5010
- NCBI Accession
- NM_005602, NP_005593
- UniProt
- O75508
- Pathways
- Hepatitis C
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