PARP3 anticorps (C-Term)

N° du produit ABIN2778113

Détail du produit anti-PARP3 anticorps

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Lapin, Cheval, Porc, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARP3 est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Séquence: LGREHHINTD NPSLKSPPPG FDSVIARGHT EPDPTQDTEL ELDGQQVVVP

Homologie: Cow: 92%, Dog: 91%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 100%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against PARP3. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 532 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-PARP3 (ABIN2778113)

Augustin, Spenlehauer, Dumond, Ménissier-De Murcia, Piel, Schmit, Apiou, Vonesch, Kock, Bornens, De Murcia: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." dans: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).

Détails sur PARP3

Antigène: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Autre désignation: PARP3 (PARP3 Produits)

Synonymes: anticorps ADPRT-3, anticorps PARP-3, anticorps PM38, anticorps Adprtl3, anticorps fj17c06, anticorps wu:fj17c06, anticorps zgc:66157, anticorps PARP3, anticorps parp3, anticorps ADPRT3, anticorps ADPRTL2, anticorps ADPRTL3, anticorps ARTD3, anticorps IRT1, anticorps PADPRT-3, anticorps A930002C11Rik, anticorps AW990611, anticorps Adprt3, anticorps pADPRT-3, anticorps seed maturation protein PM38, anticorps poly (ADP-ribose) polymerase family, member 3, anticorps poly(ADP-ribose) polymerase family member 3, anticorps poly(ADP-ribose) polymerase family member 3 L homeolog, anticorps PARP3, anticorps parp3, anticorps parp3.L, anticorps Parp3

Sujet: PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: IRT1, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
Protein Interaction Partner: UBC, APP, PARP3, HIST1H1A, PARP1, HIST2H3C, MTHFD2, HIST2H2BE, RPA3,
Protein Size: 532

Poids moléculaire: 59 kDa

ID gène: 10039

NCBI Accession: NM_005485, NP_005476

UniProt: Q9Y6F1