Asialoglycoprotein Receptor 2 anticorps (N-Term)

N° du produit ABIN2778141

Détail du produit anti-Asialoglycoprotein Receptor 2 anticorps

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Épitope: N-Term

Reactivité: Humain, Rat, Porc, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Asialoglycoprotein Receptor 2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LVVICVTGSQ SEGHRGAQLQ AELRSLKEAF SNFSSSTLTE VQAISTHGGS

Homologie: Human: 100%, Pig: 77%, Rat: 79%, Yeast: 77%

Attributs du produit: This is a rabbit polyclonal antibody against ASGR2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 311 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Asialoglycoprotein Receptor 2 (ABIN2778141)

Chang, Lai, Chien, Liang, Adak, Chuang, Chen, Lin: "Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions." dans: Bioconjugate chemistry, Vol. 24, Issue 11, pp. 1895-906, (2013) (PubMed).

Détails sur Asialoglycoprotein Receptor 2

Antigène: Asialoglycoprotein Receptor 2 (ASGR2)

Autre désignation: ASGR2 (ASGR2 Produits)

Synonymes: anticorps ASGR2, anticorps asgr2, anticorps MGC137129, anticorps ASGP-R2, anticorps ASGPR2, anticorps CLEC4H2, anticorps HBXBP, anticorps HL-2, anticorps Asgr, anticorps Asgr-2, anticorps asialoglycoprotein receptor 2, anticorps C-type lectin domain family 10 member A, anticorps ASGR2, anticorps clec10a, anticorps Asgr2, anticorps LOC100347178

Sujet: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2
Protein Interaction Partner: HDAC3, UBC, CDK6, CDK4, COPS5, TADA3, CDKN2A,
Protein Size: 311

Poids moléculaire: 35 kDa

ID gène: 433

NCBI Accession: NM_001181, NP_001172

UniProt: P07307

Pathways: Thyroid Hormone Synthesis