PLP1 anticorps (Middle Region)

N° du produit ABIN2778152

Détail du produit anti-PLP1 anticorps

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien, Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: IYGTASFFFL YGALLLAEGF YTTGAVRQIF GDYKTTICGK GLSATVTGGQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PLP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 277 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PLP1

Antigène: PLP1 (Proteolipid Protein 1 (PLP1))

Autre désignation: PLP1 (PLP1 Produits)

Synonymes: anticorps GPM6C, anticorps HLD1, anticorps MMPL, anticorps PLP, anticorps PLP/DM20, anticorps PMD, anticorps SPG2, anticorps Plp, anticorps PLP1, anticorps plp1, anticorps DKFZp459O081, anticorps DKFZp459O113, anticorps DM20, anticorps jimpy, anticorps jp, anticorps msd, anticorps rsh, anticorps plp, anticorps hld1, anticorps mmpl, anticorps plp1a, anticorps pmd, anticorps spg2, anticorps DMalpha2c, anticorps wu:fc27f01, anticorps wu:fj36d03, anticorps wu:fj42d08, anticorps zgc:110499, anticorps PLP-B, anticorps plp1-a, anticorps plp1-b, anticorps plp1b, anticorps proteolipid protein 1, anticorps proteolipid protein (myelin) 1, anticorps myelin proteolipid protein, anticorps proteolipid protein 1 L homeolog, anticorps proteolipid protein 1a, anticorps proteolipid protein 1 S homeolog, anticorps PLP1, anticorps Plp1, anticorps plp1, anticorps Tsp_11640, anticorps plp, anticorps plp1.L, anticorps plp1a, anticorps plp1.S

Sujet: PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
Protein Size: 277

Poids moléculaire: 30 kDa

ID gène: 5354

NCBI Accession: NM_000533, NP_000524

UniProt: P60201