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Cholesterol Esterase anticorps (C-Term)

CEL Reactivité: Humain, Souris, Rat, Cheval, Porc WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778160
  • Antigène Voir toutes Cholesterol Esterase (CEL) Anticorps
    Cholesterol Esterase (CEL)
    Épitope
    • 7
    • 6
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivité
    • 36
    • 12
    • 6
    • 4
    • 3
    • 2
    Humain, Souris, Rat, Cheval, Porc
    Hôte
    • 41
    • 4
    Lapin
    Clonalité
    • 41
    • 4
    Polyclonal
    Conjugué
    • 18
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Cholesterol Esterase est non-conjugé
    Application
    • 30
    • 29
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Séquence
    VTPTGDSETA PVPPTGDSGA PPVPPTGDSE AAPVPPTDDS KEAQMPAVIR
    Homologie
    Horse: 77%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against CEL. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the C - terminal region of human CEL
    Top Product
    Discover our top product CEL Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 756 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Panicot-Dubois, Thomas, Furie, Furie, Lombardo, Dubois: "Bile salt-dependent lipase interacts with platelet CXCR4 and modulates thrombus formation in mice and humans." dans: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3708-19, (2007) (PubMed).

  • Antigène
    Cholesterol Esterase (CEL)
    Autre désignation
    CEL (CEL Produits)
    Synonymes
    anticorps SC8F4.24, anticorps BAL, anticorps BSDL, anticorps BSSL, anticorps CELL, anticorps CEase, anticorps FAP, anticorps FAPP, anticorps LIPA, anticorps MODY8, anticorps 1810036E18Rik, anticorps Bal, anticorps Bssl, anticorps carboxyl ester lipase, anticorps cholesterol esterase, anticorps hypothetical protein, anticorps CEL, anticorps SCO5420, anticorps Tfu_2331, anticorps SARE_RS01070, anticorps RSal33209_1252, anticorps Caci_5976, anticorps Ndas_0054, anticorps Micau_5972, anticorps ML5_2523, anticorps Cel, anticorps cel
    Sujet
    CEL catalyzes fat and vitamin absorption. CEL acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides.The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8
    Protein Interaction Partner: OLR1, BPGM, LTF,
    Protein Size: 756
    Poids moléculaire
    80 kDa
    ID gène
    1056
    NCBI Accession
    NM_001807, NP_001798
    UniProt
    P19835
    Pathways
    Lipid Metabolism
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