KIF2A anticorps (N-Term)

N° du produit ABIN2778183

Détail du produit anti-KIF2A anticorps

Antigène: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF2A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: IEPSPETPPP PASSAKVNKI VKNRRTVASI KNDPPSRDNR VVGSARARPS

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against KIF2A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 706 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur KIF2A

Antigène: KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))

Autre désignation: KIF2A (KIF2A Produits)

Synonymes: anticorps HK2, anticorps KIF2, anticorps C530030B14Rik, anticorps Kif2, anticorps Kns2, anticorps M-kinesin, anticorps kif2-a, anticorps fj55b02, anticorps wu:fj55b02, anticorps kinesin family member 2A, anticorps kinesin heavy chain member 2A L homeolog, anticorps kinesin heavy chain member 2A, anticorps zgc:103670, anticorps Kinesin-2, anticorps KIF2A, anticorps Kif2a, anticorps kif2a.L, anticorps zgc:103670, anticorps GL50803_17333, anticorps GL50803_16456

Sujet: KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
Alias Symbols: HK2, KIF2
Protein Interaction Partner: FAM13C, MRPL53, LARP1B, KIF2A, UBC, WWOX, STK4, HIST3H3, NOTCH1, HDGF, KLC2, CLSTN1, KLC1,
Protein Size: 706

Poids moléculaire: 80 kDa

ID gène: 3796

NCBI Accession: NM_004520, NP_004511

UniProt: O00139

Pathways: Dynamique des Microtubules, Ribonucleoprotein Complex Subunit Organization