KIF3B anticorps (C-Term)

N° du produit ABIN2778187

Détail du produit anti-KIF3B anticorps

Antigène: KIF3B (Kinesin Family Member 3B (KIF3B))

Épitope: C-Term

Reactivité: Humain, Souris, Chien, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIF3B est non-conjugé

Application: Western Blotting (WB)

Séquence: APKVQAALDA ALQDEDEIQV DASSFESTAN KKSKARPKSG RKSGSSSSSS

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against KIF3B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 747 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-KIF3B (ABIN2778187)

Weisschuh, Alavi, Bonin, Wissinger: "Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach." dans: Experimental eye research, Vol. 85, Issue 4, pp. 450-61, (2007) (PubMed).

Détails sur KIF3B

Antigène: KIF3B (Kinesin Family Member 3B (KIF3B))

Autre désignation: KIF3B (KIF3B Produits)

Synonymes: anticorps FLA8, anticorps HH0048, anticorps KLP-11, anticorps AI854312, anticorps AW549267, anticorps mKIAA0359, anticorps kinesin family member 3B, anticorps KIF3B, anticorps Kif3b

Sujet: The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
Alias Symbols: PARP, PPOL, ADPRT, ADPRT1, PARP-1, ADPRT 1, pADPRT-1, KIF3B
Protein Interaction Partner: PARP1, CASP7, CASP3, UBE2I, TP53, SUMO2, CHFR, BANP, HUWE1, MDM2, SUMO3, DNMT1, CHD1L, IVNS1ABP, DDB2, PARP9, UBC, Rnf146, APLF, UHRF1, RPA3, RPA2, RPA1, ERG, MAFF, POLG2, RPL35, RPL27A, RPL19, RAD23A, PHB, CETN2, CETN1, DDX39A, PDLIM7, RPL14, MAFK, MAFG,
Protein Size: 747

Poids moléculaire: 85 kDa

ID gène: 142

NCBI Accession: NM_004798, NP_004789

UniProt: O15066

Pathways: Signalisation Hedgehog, M Phase