NCOA1 anticorps (Middle Region)
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- Antigène Voir toutes NCOA1 Anticorps
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
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Épitope
- Middle Region
- Reactivité
- Humain, Souris, Rat, Chien, Cheval, Boeuf (Vache), Cobaye, Lapin
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NCOA1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GLLHNNDRLS DGDSKYSQTS HKLVQLLTTT AEQQLRHADI DTSCKDVLSC
- Homologie
- Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against NCOA1. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human NCOA1
- Top Product
- Discover our top product NCOA1 Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 1399 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- NCOA1 (Nuclear Receptor Coactivator 1 (NCOA1))
- Autre désignation
- NCOA1 (NCOA1 Produits)
- Synonymes
- anticorps F-SRC-1, anticorps KAT13A, anticorps RIP160, anticorps SRC1, anticorps bHLHe42, anticorps bHLHe74, anticorps si:dkey-5g7.6, anticorps si:dkey-34f16.6, anticorps NCOA1, anticorps SRC-1, anticorps nuclear receptor coactivator 1, anticorps NCOA1, anticorps ncoa1, anticorps Ncoa1
- Sujet
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NCOA1 acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. NCOA1 binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion.The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: F-SRC-1, KAT13A, MGC129719, MGC129720, NCoA-1, RIP160, SRC1, bHLHe42, bHLHe74
Protein Interaction Partner: ASCC1, NR1I2, PPARG, AR, VDR, THRB, RXRA, RORB, RORA, RARA, HNF4G, NR6A1, NR5A2, ESRRA, ESR1, PAGR1, Esr2, NR3C1, CXADR, PPARA, AHR, KANK2, NCOA2, TRIM24, NCOA1, ANIB1, PGR, COPS5, UBE2L3, TP53, NCOA6, EP300, UBC, RARB, PPARD, RARG, RBBP6, CREBBP, STAT3,
Protein Size: 1399 - Poids moléculaire
- 152 kDa
- ID gène
- 8648
- NCBI Accession
- NM_147223, NP_671756
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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