UBE2N anticorps (Middle Region)

N° du produit ABIN2778258

Détail du produit anti-UBE2N anticorps

Antigène: UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

Épitope: Middle Region

Reactivité: Humain, Rat, Souris, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Mouton, Lapin, Cheval, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2N est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: VDKLGRICLD ILKDKWSPAL QIRTVLLSIQ ALLSAPNPDD PLANDVAEQW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2N. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UBE2N

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 152 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-UBE2N (ABIN2778258)

Xu, Yan, Jovanovic, An, Cheng, Aakre, Yi, Eng, Link, Moses: "Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts." dans: Proteomics, Vol. 10, Issue 13, pp. 2458-70, (2010) (PubMed).

Détails sur UBE2N

Antigène: UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))

Autre désignation: UBE2N (UBE2N Produits)

Synonymes: anticorps UBC13, anticorps UbcH-ben, anticorps UbcH13, anticorps 1500026J17Rik, anticorps AL022654, anticorps BB101821, anticorps ube2n, anticorps wu:fb11b03, anticorps wu:fc08b06, anticorps zgc:55726, anticorps ubc13, anticorps ubch-ben, anticorps UBE2N, anticorps ube2nl, anticorps zgc:63901, anticorps ubiquitin conjugating enzyme E2 N, anticorps ubiquitin-conjugating enzyme E2N, anticorps ubiquitin conjugating enzyme E2 N S homeolog, anticorps ubiquitin-conjugating enzyme E2Na, anticorps ubiquitin-conjugating enzyme E2Nb, anticorps UBE2N, anticorps Ube2n, anticorps ube2n.S, anticorps ube2na, anticorps LOC100533434, anticorps ube2n, anticorps ube2nb

Sujet: UBE2N encodes a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Alias Symbols: UBC13, UbcH-ben
Protein Interaction Partner: TRIM33, BFAR, MALT1, STUB1, BCL10, UBE2V2, UBC, TRAF6, ZNRF1, XIAP, SLX8, SLX5, MARCH7, TNF, UBE2N, RNF168, RNF8, PARK2, OTUB1, ARIH1, NEDD4L, MFN2, TRIM72, PELI3, RNF111, RNF11, BAG3, TRAF2, FN1, VCAM1, RNF126, RNF115, NBN, ATP6V1H, VPS33B, ZDHHC5, ACTR2
Protein Size: 152

Poids moléculaire: 17 kDa

ID gène: 7334

NCBI Accession: NM_003348, NP_003339

UniProt: P61088

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway