Membralin anticorps (Middle Region)

N° du produit ABIN2778282

Détail du produit anti-Membralin anticorps

Antigène: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Épitope: Middle Region

Reactivité: Poisson zèbre (Danio rerio), Humain, Cobaye, Rat, Chien, Souris, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Membralin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: YDDILMSSVK GLAENEENKG FLRNVVSGEH YRFVSMWMAR TSYLAAFAIM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against C19ORF6. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human C19ORF6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 408 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Membralin

Antigène: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Autre désignation: C19ORF6 (TMEM259 Produits)

Synonymes: anticorps ASBABP1, anticorps C19orf6, anticorps MBRL, anticorps MEMBRALIN, anticorps R32184_3, anticorps C28H19orf6, anticorps c19orf6, anticorps AC087114.7gm12, anticorps AC087114.7gm2, anticorps ORF61, anticorps mFLJ00277, anticorps Mbrl, anticorps RGD1311136, anticorps transmembrane protein 259, anticorps transmembrane protein 259 L homeolog, anticorps TMEM259, anticorps tmem259.L, anticorps Tmem259

Sujet: Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas
Alias Symbols: MBRL, ASBABP1, R32184_3, MEMBRALIN, C19ORF6
Protein Interaction Partner: ADRB2, UBC, TMEM173, ARSE,
Protein Size: 408

Poids moléculaire: 46 kDa

ID gène: 91304

NCBI Accession: NM_033420, NP_219488