ATF2 anticorps (C-Term)

N° du produit ABIN2778291

Détail du produit anti-ATF2 anticorps

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin, Chien, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: LRNEVAQLKQ LLLAHKDCPV TAMQKKSGYH TADKDDSSED ISVPSSPHTE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against ATF2. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human ATF2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 505 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur ATF2

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Autre désignation: ATF2 (ATF2 Produits)

Synonymes: anticorps CRE-BP1, anticorps CREB2, anticorps HB16, anticorps TREB7, anticorps CG12850, anticorps CG3749, anticorps dATF-2, anticorps DmelCG30420, anticorps CG30420, anticorps CHN1, anticorps Atf-2, anticorps CRE-BP, anticorps Creb2, anticorps D130078H02Rik, anticorps D18875, anticorps Tg(Gzma-Klra1)7Wum, anticorps mXBP, anticorps atf2-A, anticorps atf2l, anticorps activating transcription factor 2, anticorps Activating transcription factor-2, anticorps activating transcription factor 2 S homeolog, anticorps ATF2, anticorps Atf-2, anticorps Atf2, anticorps atf2.S, anticorps atf2

Sujet: ATF2 encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.
Alias Symbols: HB16, CREB2, TREB7, CRE-BP1
Protein Interaction Partner: MAPK10, MAPK9, MAPK8, MAPK1, SUMO1, KIFC3, FOS, MAPK14, EXOSC8, JUN, CREBBP, ATF2, CEBPG, BACH1, ATF4, ATF3, BATF3, DDIT3, BATF, FOSL1, H2AFY, RB1, GAPDH, NME2P1, TUBB, SFXN1, RAB2B, TMX1, GRPEL1, COLGALT1, AHNAK, SQRDL, RTN4, APMAP, C19orf10, RAB14, ERO1
Protein Size: 505

Poids moléculaire: 55 kDa

ID gène: 1386

NCBI Accession: NM_001880, NP_001871

Pathways: Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades