MED6 anticorps (Middle Region)

N° du produit ABIN2778336

Détail du produit anti-MED6 anticorps

Antigène: MED6 (Mediator Complex Subunit 6 (MED6))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Cobaye, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MED6 est non-conjugé

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Séquence: LLLDLRQKFP PKFVQLKPGE KPVPVDQTKK EAEPIPETVK PEEKETTKNV

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MED6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MED6

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 246 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MED6

Antigène: MED6 (Mediator Complex Subunit 6 (MED6))

Autre désignation: MED6 (MED6 Produits)

Synonymes: anticorps NY-REN-28, anticorps wu:fa14c11, anticorps zgc:86933, anticorps 1500012F11Rik, anticorps AU019660, anticorps AV213303, anticorps RNA polymerase transcriptional regulation mediator-like protein, anticorps mediator complex subunit 6, anticorps hypothetical protein, anticorps MED6, anticorps Med6, anticorps med6, anticorps CAALFM_C306170CA

Sujet: MED6 is a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. And mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
Alias Symbols: NY-REN-28
Protein Interaction Partner: TARDBP, UBC, CDK19, CDK8, MED10, MED23, CCNC, MED19, MED26, FBXW7, MED11, MED28, MED29, MED4, MED12, MED7, MED21, MED1, SMARCA4, BCL6, SUZ12, CUL1, SKP1, CTDP1, MED25, SREBF1, MED15, VDR, OBFC1, MED18, ZC3H13, TADA2A, RARA, PARP1, SMAD3, SMAD2, SMAD1, MED
Protein Size: 246

Poids moléculaire: 28 kDa

ID gène: 10001

NCBI Accession: NM_005466, NP_005457

UniProt: O75586

Pathways: Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha