Afadin anticorps (N-Term)

N° du produit ABIN2778340

Détail du produit anti-Afadin anticorps

Antigène: Afadin (MLLT4)

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Boeuf (Vache), Cobaye, Cheval, Lapin, Porc, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Afadin est non-conjugé

Application: Western Blotting (WB)

Séquence: GVIQNFKRTL SKKEKKEKKK REKEALRQAS DKDDRPFQGE DVENSRLAAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 100%, Yeast: 92%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against MLLT4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 674 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Afadin

Antigène: Afadin (MLLT4)

Autre désignation: MLLT4 (MLLT4 Produits)

Synonymes: anticorps MLLT4, anticorps af-6, anticorps af6, anticorps si:ch211-278j12.1, anticorps AF6, anticorps RP3-431P23.3, anticorps 5033403D15Rik, anticorps Af-6, anticorps Afadin, anticorps Gm314, anticorps I-afadin, anticorps S-afadin, anticorps Af6, anticorps afadin, adherens junction formation factor, anticorps afadin, adherens junction formation factor L homeolog, anticorps afadin, adherens junction formation factor a, anticorps afadin, anticorps AFDN, anticorps afdn.L, anticorps afdna, anticorps LOC589923, anticorps LOC100177180, anticorps afdn, anticorps Afdn

Sujet: AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t(6,11) translocations.
Alias Symbols: RP3-470B24.4, AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3
Protein Interaction Partner: UBC, LGR4, LATS2, YWHAQ, YWHAE, VCAM1, SMAD2, ITGA4, GRB2, FN1, SIRT7, HNRNPA1, ARRB2, YWHAG, YWHAB, KMT2A, MEN1, PVRL4, PICK1, RIT2, SORBS2, F11R, NRXN2, SSX2IP, RIT1, NRXN3, PVRL3, PVRL1, MRAS, SORBS1, EPHB6, EPHA7, JAG1, EPHB3, RALGDS, TJP1, EPHB2, PVR
Protein Size: 674

Poids moléculaire: 74 kDa

ID gène: 4301

NCBI Accession: NM_001040000

UniProt: P55196

Pathways: Cell-Cell Junction Organization