PML anticorps (Middle Region)
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- Antigène Voir toutes PML Anticorps
- PML (Promyelocytic Leukemia (PML))
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Épitope
- Middle Region
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PML est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- TTLPPAQPAF NLQALGTYFE GLLEGPALAR AEGVSTPLAG RGLAERASQQ
- Specificité
- Isoform 1, 9, 10 and 11 specific
- Homologie
- Human: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PML. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human PML
- Top Product
- Discover our top product PML Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 882 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- PML (Promyelocytic Leukemia (PML))
- Autre désignation
- PML (PML Produits)
- Synonymes
- anticorps MYL, anticorps PP8675, anticorps RNF71, anticorps TRIM19, anticorps 1200009E24Rik, anticorps AI661194, anticorps Trim19, anticorps RGD1562602, anticorps PML, anticorps promyelocytic leukemia, anticorps PML, anticorps Pml
- Sujet
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PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor an
Alias Symbols: MYL, PP8675, RNF71, TRIM19
Protein Interaction Partner: RPL11, RPL5, SUMO1, UBC, TP53, SUMO2, SUMO3, MDM2, RNF4, EGFR, NCOA2, SP100, DAXX, MAPK7, HDAC1, ATXN1, ATRX, ASF1A, EHMT2, HIRA, HTT, H3F3A, ATF7IP, PML, JAK1, EIF4E, GLIS2, UBE2I, smt3, HDAC11, HDAC6, LMNA, RNF111, CDK6, CDK2, CDK1, CASP8AP2, RBX1, SH3G
Protein Size: 882 - Poids moléculaire
- 97 kDa
- ID gène
- 5371
- NCBI Accession
- NM_033238, NP_150241
- UniProt
- P29590
- Pathways
- Signalisation p53, Retinoic Acid Receptor Signaling Pathway, Maintenance of Protein Location, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus
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