RNF8 anticorps (C-Term)

N° du produit ABIN2778597

Détail du produit anti-RNF8 anticorps

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Cheval, Lapin, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNF8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 485 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RNF8

Antigène: RNF8 (Ring Finger Protein 8 (RNF8))

Autre désignation: RNF8 (RNF8 Produits)

Synonymes: anticorps hRNF8, anticorps 3830404E21Rik, anticorps AIP37, anticorps RNF8, anticorps rnf8, anticorps fc66f09, anticorps wu:fc66f09, anticorps zgc:55936, anticorps zgc:77313, anticorps ring finger protein 8, anticorps ring finger protein 8, E3 ubiquitin protein ligase S homeolog, anticorps ring finger protein 8, E3 ubiquitin protein ligase L homeolog, anticorps ring finger protein 8, E3 ubiquitin protein ligase, anticorps RNF8, anticorps Rnf8, anticorps rnf8.S, anticorps rnf8.L, anticorps rnf8

Sujet: RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ12013, KIAA0646
Protein Interaction Partner: TMEM79, HOMEZ, SEPT3, RBFOX2, PNMA2, USP16, WASL, HERC2, MAD1L1, VCP, TNFRSF1A, TNF, BCL10, UBE2N, UBC, NEDD8, JMJD1C, MDC1, EXOSC2, MDM2, BLM, SEPT8, SEPT7, RPSA, H2AFX, RL2, HIST2H2BE, HIST2H2AC, PCNA, RAD50, NBN, MRE11A, UBE2E3, UBE2V1, UBE2E2, UBE2E1,
Protein Size: 485

Poids moléculaire: 55 kDa

ID gène: 9025

NCBI Accession: NM_003958, NP_003949

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response