Kdm6b anticorps (Middle Region)

N° du produit ABIN2778611

Détail du produit anti-Kdm6b anticorps

Antigène: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Lapin, Boeuf (Vache), Cheval, Porc

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Kdm6b est non-conjugé

Application: Western Blotting (WB)

Séquence: AGLQGVVVLE QYRTEELAQA YDAFTLVRAR RARGQRRRAL GQAAGTGFGS

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against JMJD3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human JMJD3

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 644 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Kdm6b

Antigène: Kdm6b (Lysine (K)-Specific Demethylase 6B (Kdm6b))

Autre désignation: JMJD3 (Kdm6b Produits)

Synonymes: anticorps jmjd3, anticorps kdm6b, anticorps si:ch211-237l4.7, anticorps 1700064E03Rik, anticorps BC038313, anticorps Jmjd3, anticorps mKIAA0346, anticorps JMJD3, anticorps lysine (K)-specific demethylase 6B, anticorps lysine demethylase 6B, anticorps lysine (K)-specific demethylase 6B, b, anticorps KDM1 lysine (K)-specific demethylase 6B, anticorps kdm6b, anticorps KDM6B, anticorps kdm6bb, anticorps Kdm6b

Sujet: JMJD3 is a histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code. It plays a central role in regulation of posterior development, by regulating HOX gene expression. It is involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.
Alias Symbols: KIAA0346, JMJD3
Protein Interaction Partner: WDR5, ASH2L, RBBP5, UBC, TK1, CSNK2B, HIST1H3A, WAS, SMAD3, SMAD2, SMAD4, SMAD1,
Protein Size: 1643

Poids moléculaire: 177 kDa

ID gène: 23135

NCBI Accession: NM_001080424

UniProt: O15054

Pathways: L'effet Warburg