RPL8 anticorps (C-Term)

N° du produit ABIN2778675

Détail du produit anti-RPL8 anticorps

Antigène: RPL8 (Ribosomal Protein L8 (RPL8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Cobaye, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RPL8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: KKVISSANRA VVGVVAGGGR IDKPILKAGR AYHKYKAKRN CWPRVRGVAM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RPL8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human RPL8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 257 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RPL8 (ABIN2778675)

Wong, Traynor, Basse, Kay, Warren: "Defective ribosome assembly in Shwachman-Diamond syndrome." dans: Blood, Vol. 118, Issue 16, pp. 4305-12, (2011) (PubMed).

Détails sur RPL8

Antigène: RPL8 (Ribosomal Protein L8 (RPL8))

Autre désignation: RPL8 (RPL8 Produits)

Synonymes: anticorps L8, anticorps zgc:73105, anticorps zgc:77641, anticorps CG1263, anticorps Dmel\\CG1263, anticorps M(3)62F, anticorps M(3)LS2, anticorps Rp L8, anticorps anon-EST:Posey5, anticorps rpL8, anticorps RPL8, anticorps ribosomal protein L8, anticorps ribosomal protein L8 S homeolog, anticorps Ribosomal protein L8, anticorps microRNA 6850, anticorps RPL8, anticorps Rpl8, anticorps rpl8.S, anticorps rpl8, anticorps RpL8, anticorps MIR6850

Sujet: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL8 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: L8
Protein Interaction Partner: TP53, HUWE1, SUMO2, TUBGCP3, CEP250, STAU1, UBC, MDM2, ZBTB1, EED, RPS25, RPL28, PARK2, FBXO6, UPF2, TARDBP, ICAM1, IGSF8, PAN2, ITGA4, IL7R, FN1, DPH3, UBL4A, VCAM1, EIF4A3, PA2G4, MAGOH, ESR1, RPLP0P6, RPL10L, TUBA1C, ATF7IP, RPL36, TXN2, PPT2, RPL23, R
Protein Size: 257

Poids moléculaire: 28 kDa

ID gène: 6132

NCBI Accession: NM_000973, NP_000964

UniProt: P62917

Pathways: Regulation of Cell Size