DAZ2 anticorps (N-Term)

N° du produit ABIN2778701

Détail du produit anti-DAZ2 anticorps

Antigène: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Épitope: N-Term

Reactivité: Humain, Souris, Boeuf (Vache), Chien, Chévre, Cobaye, Cheval, Lapin, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAZ2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MDETEIGSCF GRYGSVKEVK IITNRTGVSK GYGFVSFVND VDVQKIVGSQ

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against DAZ2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human DAZ2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 534 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur DAZ2

Antigène: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Autre désignation: DAZ2 (DAZ2 Produits)

Synonymes: anticorps pDP1678, anticorps DAZ2, anticorps deleted in azoospermia 2, anticorps deleted in azoospermia protein 2, anticorps DAZ2, anticorps LOC738583

Sujet: DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: pDP1678
Protein Interaction Partner: UBC, PUM2,
Protein Size: 534

Poids moléculaire: 59 kDa

ID gène: 57055

NCBI Accession: NM_001005785, NP_001005785

UniProt: Q2KHN6