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SNRNP70 anticorps (N-Term)

SNRNP70 Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778715
  • Antigène Voir toutes SNRNP70 Anticorps
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    Épitope
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 23
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Humain, Souris, Rat, Chien, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval
    Hôte
    • 23
    Lapin
    Clonalité
    • 23
    Polyclonal
    Conjugué
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp SNRNP70 est non-conjugé
    Application
    • 23
    • 14
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    PHNDPNAQGD AFKTLFVARV NYDTTESKLR REFEVYGPIK RIHMVYSKRS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot and immunohistochemistry.
    Purification
    Affinity Purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SNRP70
    Top Product
    Discover our top product SNRNP70 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 437 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wang, Mueller, Hertel, Cambi: "G Run-mediated recognition of proteolipid protein and DM20 5' splice sites by U1 small nuclear RNA is regulated by context and proximity to the splice site." dans: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4059-71, (2011) (PubMed).

    Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." dans: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

  • Antigène
    SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))
    Autre désignation
    SNRP70 (SNRNP70 Produits)
    Synonymes
    anticorps rnpu1z, anticorps rpu1, anticorps snrp70, anticorps u170k, anticorps u1ap, anticorps u1rnp, anticorps SNRP70, anticorps wu:fc20b04, anticorps zgc:136450, anticorps 2700022N21Rik, anticorps 3200002N22Rik, anticorps 70kDa, anticorps AI325098, anticorps R74807, anticorps Rnulp70, anticorps Snrp70, anticorps Srnp70, anticorps U1-70, anticorps U1-70K, anticorps RNPU1Z, anticorps RPU1, anticorps Snp1, anticorps U170K, anticorps U1AP, anticorps U1RNP, anticorps small nuclear ribonucleoprotein, U1 70kDa subunit, anticorps small nuclear ribonucleoprotein U1 subunit 70, anticorps small nuclear ribonucleoprotein 70 (U1), anticorps small nuclear ribonucleoprotein, U1 70kDa subunit L homeolog, anticorps snrnp70, anticorps SNRNP70, anticorps Snrnp70, anticorps snrnp70.L
    Sujet
    SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
    Alias Symbols: RPU1, Snp1, U1AP, U170K, U1RNP, RNPU1Z, SNRP70, U1-70K
    Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
    Protein Size: 437
    Poids moléculaire
    52 kDa
    ID gène
    6625
    NCBI Accession
    NM_003089, NP_003080
    UniProt
    P08621
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