Retinoic Acid Receptor alpha anticorps (N-Term)

N° du produit ABIN2778741

Cet anticorps anti-Retinoic Acid Receptor alpha Polyclonal Lapin (ABIN2778741) détecte spécifiquement Retinoic Acid Receptor alpha dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Retinoic Acid Receptor alpha anticorps (N-Term) (ABIN2778741)

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoic Acid Receptor alpha est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Retinoic Acid Receptor alpha anticorps

Épitope: N-Term

Séquence: TPNPFLVVDF YNQNRACLLP EKGLPAPGPY STPLRTPLWN GSNHSIETQS

Homologie: Human: 100%, Mouse: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against RARA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RARA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 457 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Retinoic Acid Receptor alpha

Antigène: Retinoic Acid Receptor alpha (RARA) (Retinoic Acid Receptor, alpha (RARA))

Autre désignation: RARA

Sujet: RARA contains 1 nuclear receptor DNA-binding domain and belongs to the nuclear hormone receptor family, NR1 subfamily. It is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression
Alias Symbols: RAR, NR1B1
Protein Interaction Partner: NCOR2, NCOR1, RXRG, MED1, HDAC1, NRIP1, TEKT4, NSD1, NCOA1, CEBPA, ITGB1BP2, SUMO1, UBC, MBD3, CBX5, MTA2, E2F1, WWOX, Sumo2, RXRB, RXRA, AKT1, MMS19, Dlg4, TMEM54, FN1, USP7, NCOA2, SUZ12, EZH2, PML, PSMC5, FAS, PRAM1, TBL1XR1, PRAME, ARID5A, UBE3A, UBQL
Protein Size: 457

Poids moléculaire: 50 kDa

ID gène: 5914

NCBI Accession: NM_001024809, NP_001019980

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, S100 Proteins