Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) anticorps
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- Antigène Voir toutes Splicing factor U2AF 26 kDa subunit (U2AF1L4) Anticorps
- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
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Épitope
- N-Term
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Reactivité
- Humain, Chien, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Lapin, Poisson zèbre (Danio rerio), Chévre
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Inconjugué
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Application
- Western Blotting (WB)
- Séquence
- KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
- Homologie
- Cow: 100%, Dog: 100%, Goat: 79%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against U2AF1L4. It was validated on Western Blot.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human U2AF1L4
- Top Product
- Discover our top product U2AF1L4 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Splicing factor U2AF 26 kDa subunit (U2AF1L4)
- Autre désignation
- U2AF1L4 (U2AF1L4 Produits)
- Synonymes
- anticorps U2 small nuclear RNA auxiliary factor 1-like protein 3, anticorps U2AF1-RS3, anticorps U2AF1-like 4, anticorps U2AF1-like protein 3, anticorps U2AF1L3, anticorps U2AF1L3V1, anticorps U2AF1RS3, anticorps U2af26, anticorps AA407033, anticorps AF419339, anticorps AI451269, anticorps AW553050, anticorps TMEM149, anticorps U2 small nuclear RNA auxiliary factor 1 like 4, anticorps U2 small nuclear RNA auxiliary factor 1-like 4, anticorps U2AF1L4, anticorps U2af1l4
- Sujet
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U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.
Protein Interaction Partner: MDM2, SUZ12, UBC, ELAVL1, GIGYF2,
Protein Size: 220 - Poids moléculaire
- 24 kDa
- ID gène
- 199746
- UniProt
- Q8WU68
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