CELF1 anticorps (Middle Region)

N° du produit ABIN2778749

Détail du produit anti-CELF1 anticorps

Antigène: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Lapin, Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: QMKPADSEKN NVEDRKLFIG MISKKCTEND IRVMFSSFGQ IEECRILRGP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CUGBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CUGBP1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 512 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CELF1

Antigène: CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))

Autre désignation: CUGBP1 (CELF1 Produits)

Sujet: Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene.
Alias Symbols: BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Protein Interaction Partner: UBC, MDM2, RPA3, RPA2, RPA1, BMI1, TARDBP, RALY, HNRNPC, APP, ELAVL1, SUMO2, USP10, FUBP1, PPBP, DMPK, TOM1L1, CELF1,
Protein Size: 512

Poids moléculaire: 56 kDa

ID gène: 10658

NCBI Accession: NM_001172639, NP_001166110

Pathways: Ribonucleoprotein Complex Subunit Organization