EIF4B anticorps (C-Term)

N° du produit ABIN2778771

Détail du produit anti-EIF4B anticorps

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF4B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: NPPARSQSSD TEQQSPTSGG GKVAPAQPSE EGPGRKDENK VDGMNAPKGQ

Homologie: Cow: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Attributs du produit: This is a rabbit polyclonal antibody against EIF4B. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 611 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-EIF4B (ABIN2778771)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." dans: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Détails sur EIF4B

Antigène: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Autre désignation: EIF4B (EIF4B Produits)

Synonymes: anticorps EIF-4B, anticorps PRO1843, anticorps CG10837, anticorps Dm-eIF4B, anticorps Dmel\\CG10837, anticorps Eif4B, anticorps eIF-4B-L, anticorps eIF-4B-S, anticorps eIF-4b, anticorps eIF4B, anticorps eIF4B-L, anticorps eIF4B-S, anticorps eIf4b, anticorps 2310046H11Rik, anticorps AL024095, anticorps C85189, anticorps Eif4a2, anticorps eif4b, anticorps fb15c09, anticorps wu:fb15c09, anticorps zgc:101532, anticorps MGC89384, anticorps eukaryotic translation initiation factor 4B, anticorps eukaryotic initiation factor 4B, anticorps Eukaryotic initiation factor 4B, anticorps eukaryotic translation initiation factor 4Bb, anticorps eukaryotic translation initiation factor 4Ba, anticorps eukaryotic translation initiation factor 4B S homeolog, anticorps EIF4B, anticorps Eif4B, anticorps eIF-4B, anticorps Eif4b, anticorps eif4bb, anticorps eif4b, anticorps eif4ba, anticorps eif4b.S, anticorps LOC100284982, anticorps LOC100380867

Sujet: IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Alias Symbols: EIF-4B, PRO1843
Protein Interaction Partner: UBC, ASB2, ZBTB1, SAMHD1, XPO7, SEC23A, PRMT3, CUL4B, USP11, SF1, XRCC5, OSBP, NARS, Stk11, CTNNA1, PARK2, FBXO6, PAN2, CSNK2A1, EIF4A3, YWHAE, MAGOH, SMURF1, NUP107, PHAX, SLC4A1AP, CCT6B, NUP153, POLR1C, RPL29, MYH9, EIF4G2, EIF4G1, EIF4A1, CSTF2, CUL3,
Protein Size: 611

Poids moléculaire: 67 kDa

ID gène: 1975

NCBI Accession: NM_001417, NP_001408

UniProt: P23588