EIF4E anticorps (C-Term)
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- Antigène Voir toutes EIF4E Anticorps
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
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Épitope
- C-Term
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Reactivité
- Humain, Rat, Souris, Poisson zèbre (Danio rerio), Boeuf (Vache), Lapin, Chien, Cobaye, Cheval
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF4E est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- TECENREAVT HIGRVYKERL GLPPKIVIGY QSHADTATKS GSTTKNRFVV
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against EIF4E. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4E
- Top Product
- Discover our top product EIF4E Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 217 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))
- Autre désignation
- EIF4E (EIF4E Produits)
- Synonymes
- anticorps AUTS19, anticorps CBP, anticorps EIF4E1, anticorps EIF4EL1, anticorps EIF4F, anticorps eif4e-1, anticorps zgc:86680, anticorps EG668879, anticorps Eif4e-ps, anticorps If4e, anticorps eIF-4E, anticorps 0260/09, anticorps 0587/11, anticorps 0589/11, anticorps 0919/12, anticorps 1004/13, anticorps 2, anticorps 7238, anticorps CG4035, anticorps CT13384, anticorps CT39424, anticorps CT39426, anticorps D-eIF4E, anticorps Dmel\\CG4035, anticorps Eif4E, anticorps Eif4e, anticorps IF4E, anticorps dEif4e, anticorps deIF-4E, anticorps deIF4E, anticorps eIF 4E, anticorps eIF-4E1, anticorps eIF-4E2, anticorps eIF-4EII, anticorps eIF-4e, anticorps eIF4E, anticorps eIF4E-1, anticorps eIF4E-1/2, anticorps eIF4E-2, anticorps eIF4E1, anticorps eIF4EI, anticorps eIF4e, anticorps eif-4E, anticorps eif-4e, anticorps eif4e, anticorps l(3)07238, anticorps l(3)67Af, anticorps l(3)S025007, anticorps l(3)S026009, anticorps l(3)S058711, anticorps l(3)S091912, anticorps cbp, anticorps eif4f, anticorps eif4e1, anticorps eif4el1, anticorps EIF-4E, anticorps zgc:101581, anticorps eukaryotic translation initiation factor 4E, anticorps eukaryotic translation initiation factor 4ea, anticorps Eukaryotic initiation factor 4E, anticorps eucaryotic initiation factor 6, anticorps eukaryotic translation initiation factor 4E L homeolog, anticorps eukaryotic translation initiation factor 4E family member 1B S homeolog, anticorps translation initiation factor eIF4E, anticorps eukaryotic translation initiation factor 4eb, anticorps EIF4E, anticorps eif4ea, anticorps Eif4e, anticorps eIF-4E, anticorps eif6, anticorps eif4e, anticorps eif4e.L, anticorps eif4e1b.S, anticorps LOC100533326, anticorps eif4eb
- Sujet
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All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CBP, EIF4E1, EIF4EL1, EIF4F, MGC111573
Protein Interaction Partner: EIF4EBP1, UBXN11, EIF4ENIF1, KANK2, TRIM22, EIF4EBP3, TDO2, TRIM27, EIF4G1, EIF4EBP2, EIF3B, RPS6KB1, MTOR, PML, NANS, PROSC, AHSA1, PEPD, EIF6, HSPD1, HSPA9, TYMP, CAPN1, ASS1, GEMIN5, PRDM4, CD83, UBC, ITGA4, APP, EIF4H, RPTOR, EIF4A1, RPS6KA5, HSPB2, E
Protein Size: 217 - Poids moléculaire
- 25 kDa
- ID gène
- 1977
- NCBI Accession
- NM_001968, NP_001959
- UniProt
- P06730
- Pathways
- BCR Signaling
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