ISG20 anticorps (N-Term)

N° du produit ABIN2778795

Détail du produit anti-ISG20 anticorps

Antigène: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Épitope: N-Term

Reactivité: Humain, Rat, Souris, Chien, Cheval, Boeuf (Vache), Porc, Cobaye, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISG20 est non-conjugé

Application: Western Blotting (WB)

Séquence: GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 181 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-ISG20 (ABIN2778795)

Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." dans: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." dans: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

Détails sur ISG20

Antigène: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Autre désignation: ISG20 (ISG20 Produits)

Synonymes: anticorps ISG20, anticorps CD25, anticorps HEM45, anticorps 1600023I01Rik, anticorps 2010107M23Rik, anticorps 20kDa, anticorps DnaQL, anticorps interferon stimulated exonuclease gene 20, anticorps interferon-stimulated protein, anticorps ISG20, anticorps Isg20

Sujet: ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
Alias Symbols: CD25, HEM45
Protein Interaction Partner: UBC,
Protein Size: 181

Poids moléculaire: 20 kDa

ID gène: 3669

NCBI Accession: NM_002201, NP_002192

UniProt: Q96AZ6