PPP1R8 anticorps (Middle Region)

N° du produit ABIN2778806

Détail du produit anti-PPP1R8 anticorps

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP1R8 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK

Specificité: This antibody recognizes isoform-gamma

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against PPP1R8. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PPP1R8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 127 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PPP1R8

Antigène: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Autre désignation: PPP1R8 (PPP1R8 Produits)

Synonymes: anticorps ARD-1, anticorps ARD1, anticorps NIPP-1, anticorps NIPP1, anticorps PRO2047, anticorps 6330548N22Rik, anticorps AU044684, anticorps PPP1R8, anticorps ard-1, anticorps ard1, anticorps nipp-1, anticorps nipp1, anticorps ppp1r8, anticorps si:ch211-206a7.1, anticorps protein phosphatase 1 regulatory subunit 8, anticorps protein phosphatase 1, regulatory subunit 8, anticorps protein phosphatase 1, regulatory (inhibitor) subunit 8, anticorps protein phosphatase 1, regulatory subunit 8b, anticorps protein phosphatase 1 regulatory subunit 8 L homeolog, anticorps protein phosphatase 1, regulatory subunit 8a, anticorps protein phosphatase 1 regulatory subunit 8 S homeolog, anticorps PPP1R8, anticorps Ppp1r8, anticorps ppp1r8b, anticorps ppp1r8.L, anticorps ppp1r8a, anticorps ppp1r8.S

Sujet: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD1, ARD-1, NIPP1, NIPP-1, PRO2047
Protein Interaction Partner: APPBP2, UBC, FBXO25, HMGA1, WDR77, CTNNBL1, PPIL1, PPP1CC, PPP1CA, NF2, APP, SF3A2, Cep72, PPP1CB, SUZ12, RBBP4, EZH2, EED, RBM48, SF3B1, SETDB1, MELK, HDAC2, C14orf1, STC2, CDC5L, CRMP1, PRKACA, GBP2, LYN, CSNK2A2, CSNK2A1, NME2,
Protein Size: 127

Poids moléculaire: 14 kDa

ID gène: 5511

NCBI Accession: NM_002713, NP_002704

UniProt: Q12972