RDBP anticorps (N-Term)

N° du produit ABIN2778822

Détail du produit anti-RDBP anticorps

Antigène: RDBP (RD RNA Binding Protein (RDBP))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cheval, Boeuf (Vache), Cobaye, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RDBP est non-conjugé

Application: Western Blotting (WB)

Séquence: LVIPPGLSEE EEALQKKFNK LKKKKKALLA LKKQSSSSTT SQGGVKRSLS

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Attributs du produit: This is a rabbit polyclonal antibody against RDBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RDBP

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 380 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RDBP (ABIN2778822)

Schulz, Brandner, Eberhagen, Eckardt-Schupp, Larsen, Andrae: "Quantitative phosphoproteomic analysis of early alterations in protein phosphorylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin." dans: Journal of proteome research, Vol. 12, Issue 2, pp. 866-82, (2013) (PubMed).

Détails sur RDBP

Antigène: RDBP (RD RNA Binding Protein (RDBP))

Autre désignation: RDBP (RDBP Produits)

Synonymes: anticorps CG5994, anticorps Dmel\\CG5994, anticorps NELF, anticorps NELF-E, anticorps Nelf-e, anticorps anon-66Da, anticorps cg5994, anticorps dNelf-E, anticorps D6S45, anticorps RD, anticorps RDBP, anticorps RDP, anticorps Rd, anticorps Rdbp, anticorps D17H6S45, anticorps Negative elongation factor E, anticorps negative elongation factor complex member E, anticorps negative elongation factor complex member E, Rdbp, anticorps Nelf-E, anticorps NELFE, anticorps Nelfe

Sujet: RDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D).The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: D6S45, NELF-E, RD, RDP, RDBP
Protein Interaction Partner: CCDC57, MTUS2, TRIM27, UBC, SRPK2, SRPK1, LMNA, POLR2C, SUMO1, NELFCD, NELFB, SF3B1, NELFA, TMEM141, RPAP2, WDR48, VAMP3, NCOR1, NELFE, POLR2A, CACTIN,
Protein Size: 380

Poids moléculaire: 43 kDa

ID gène: 7936

NCBI Accession: NM_002904, NP_002895

UniProt: P18615