SNRPA1 anticorps (Middle Region)

N° du produit ABIN2778901

Détail du produit anti-SNRPA1 anticorps

Antigène: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Mouton, Cobaye, Cheval, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNRPA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: MPGQMPPAQP LSENPPNHIL FLTNLPEETN ELMLSMLFNQ FPGFKEVRLV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SNRPA. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SNRPA

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 282 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SNRPA1 (ABIN2778901)

Wang, Cambi: "Heterogeneous nuclear ribonucleoproteins H and F regulate the proteolipid protein/DM20 ratio by recruiting U1 small nuclear ribonucleoprotein through a complex array of G runs." dans: The Journal of biological chemistry, Vol. 284, Issue 17, pp. 11194-204, (2009) (PubMed).

Détails sur SNRPA1

Antigène: SNRPA1 (SNRPA) (Small Nuclear Ribonucleoprotein Polypeptide A (SNRPA))

Autre désignation: SNRPA (SNRPA Produits)

Synonymes: anticorps Mud1, anticorps U1-A, anticorps U1A, anticorps im:7142962, anticorps zgc:101832, anticorps C430021M15Rik, anticorps Rnu1a-1, anticorps Rnu1a1, anticorps mud1, anticorps snf, anticorps fc19d01, anticorps wu:fc19d01, anticorps zgc:77810, anticorps T30B22.12, anticorps U1SNRNP-SPECIFIC PROTEIN, anticorps spliceosomal protein U1A, anticorps small nuclear ribonucleoprotein polypeptide A, anticorps small nuclear ribonucleoprotein polypeptide A', anticorps small nuclear ribonucleoprotein polypeptide A S homeolog, anticorps spliceosomal protein U1A, anticorps SNRPA, anticorps snrpa1, anticorps Snrpa, anticorps snrpa.S, anticorps snrpa, anticorps U1A

Sujet: SNRPA binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process.
Alias Symbols: U1A, Mud1, U1-A
Protein Interaction Partner: LENG8, METTL13, RBMX, NDUFAF3, MTUS2, U2AF2, ENOX2, QKI, SNRPA1, SNRPA, SFPQ, TRIM27, RBM3, PTBP1, PCBP2, PCBP1, HNRNPK, GABPB1, CIRBP, UBC, LIN28B, LIN28A, RNF2, EZH2, SUZ12, EED, PRKDC, GIT1, WBP4, CDKN2A, SRPK2, SRPK3, C19orf43, TP63, SMAD5, IL7R, IFIT
Protein Size: 282

Poids moléculaire: 31 kDa

ID gène: 6626

NCBI Accession: NM_004596, NP_004587

UniProt: P09012