AIMP1 anticorps (N-Term)

N° du produit ABIN2778912

Détail du produit anti-AIMP1 anticorps

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Lapin, Poisson zèbre (Danio rerio), Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIMP1 est non-conjugé

Application: Western Blotting (WB)

Séquence: LLKEKAILQA TLREEKKLRV ENAKLKKEIE ELKQELIQAE IQNGVKQIPF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SCYE1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human SCYE1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 312 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-AIMP1 (ABIN2778912)

Tandle, Mazzanti, Alexander, Roberts, Libutti: "Endothelial monocyte activating polypeptide-II induced gene expression changes in endothelial cells." dans: Cytokine, Vol. 30, Issue 6, pp. 347-58, (2005) (PubMed).

Détails sur AIMP1

Antigène: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Autre désignation: SCYE1 (AIMP1 Produits)

Synonymes: anticorps EMAP2, anticorps EMAPII, anticorps HLD3, anticorps SCYE1, anticorps p43, anticorps wu:fa95a05, anticorps zgc:154081, anticorps AIMP1, anticorps 9830137A06Rik, anticorps AIMP1/p43, anticorps Emap2, anticorps Scye1, anticorps scye1, anticorps aminoacyl tRNA synthetase complex interacting multifunctional protein 1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 1, anticorps aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 S homeolog, anticorps AIMP1, anticorps aimp1, anticorps Aimp1, anticorps aimp1.S

Sujet: SCYE1 is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.The protein encoded by this gene is a cytokine that is specifically induced by apoptosis. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor of SCYE1 (pro-SCYE1) is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex. Therefore, pro-SCYE1 may function in binding RNA as part of the tRNA synthetase complex in normal cells and in stimulating inflammatory responses after proteolytic cleavage in tumor cells.
Alias Symbols: p43, HLD3, EMAP2, SCYE1, EMAPII
Protein Interaction Partner: AIMP2, TSNAX, UBC, CCAR2, RPL36, EEF1E1, IQGAP1, VARS, RPLP0, RPL27A, RPL23A, RPL21, RPL17, RPL15, RPL13, RPL7A, RARS, QARS, PTBP1, PSMC6, MARS, KARS, IARS, DNAJA1, EIF4G1, EIF2S3, EIF2S1, DARS, PAN2, gag, HSP90B1, MAPK8, LARS, EPRS, APP, COPS5, CUL1, PSM
Protein Size: 312

Poids moléculaire: 34 kDa

ID gène: 9255

NCBI Accession: NM_004757, NP_004748

UniProt: Q12904