PCBP2 anticorps (N-Term)
-
- Antigène Voir toutes PCBP2 Anticorps
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Poisson zèbre (Danio rerio), Cobaye, Cheval, Chien, Lapin
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp PCBP2 est non-conjugé
-
Application
- Western Blotting (WB)
- Séquence
- KKGESVKKMR EESGARINIS EGNCPERIIT LAGPTNAIFK AFAMIIDKLE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against PCBP2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Protein A purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PCBP2
- Top Product
- Discover our top product PCBP2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 366 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- PCBP2 (Poly(rC) Binding Protein 2 (PCBP2))
- Autre désignation
- PCBP2 (PCBP2 Produits)
- Synonymes
- anticorps HNRNPE2, anticorps HNRPE2, anticorps hnRNP-E2, anticorps AW412548, anticorps Hnrpx, anticorps alphaCP-2, anticorps PCBP3, anticorps fb36h02, anticorps wu:fb36h02, anticorps zgc:55964, anticorps PCBP2, anticorps poly(rC) binding protein 2, anticorps poly(rC) binding protein 2 L homeolog, anticorps PCBP2, anticorps Pcbp2, anticorps pcbp2, anticorps pcbp2.L
- Sujet
-
PCBP2 appears to be multifunctional. It along with PCBP-1 and hnRNPK corresponds to the major cellular poly(rC)-binding proteins. This protein together with PCBP-1 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This gene and PCBP-1 has paralogues PCBP3 and PCBP4 which is thought to arose as a result of duplication events of entire genes.The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HNRPE2, MGC110998, hnRNP-E2
Protein Interaction Partner: FUS, HUWE1, UBC, SNRPA, SUMO2, SUMO3, CEP250, MDM2, EED, TARDBP, ADRB2, IGSF8, HMGA1, CD81, HMGA2, WDR83, SLU7, CASK, UBL4A, VCAM1, PCBP2, NOS2, ITGA4, FN1, BRCA1, PRPF40A, SF3B2, NKAP, WDR77, PAXIP1, BARD1, PPIB, EEF1A1, FBXO6, UBD, PCBP1, QKI, CDK2, COP
Protein Size: 366 - Poids moléculaire
- 39 kDa
- ID gène
- 5094
- NCBI Accession
- NM_005016, NP_005007
- UniProt
- Q6IPF4
-