Nucleolin anticorps (N-Term)

N° du produit ABIN2778935

Détail du produit anti-Nucleolin anticorps

Antigène: Nucleolin (NCL)

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien, Lapin, Cheval, Saccharomyces cerevisiae, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Nucleolin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: GKALVATPGK KGAAIPAKGA KNGKNAKKED SDEEEDDDSE EDEEDDEDED

Homologie: Cow: 87%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 91%, Pig: 86%, Rabbit: 77%, Rat: 93%, Yeast: 83%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against NCL. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human NCL

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 710 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-Nucleolin (ABIN2778935)

Shefer, Boulos, Gotea, Arafat, Ben Chaim, Muharram, Isaac, Eden, Sperling, Elnitski, Sperling: "A novel role for nucleolin in splice site selection." dans: RNA biology, Vol. 19, Issue 1, pp. 333-352, (2022) (PubMed).

Détails sur Nucleolin

Antigène: Nucleolin (NCL)

Autre désignation: NCL (NCL Produits)

Sujet: Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.Nucleolin (NCL), a eukaryotic nucleolar phosphoprotein, is involved in the synthesis and maturation of ribosomes. It is located mainly in dense fibrillar regions of the nucleolus. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. The intron 11 of the NCL gene encodes a small nucleolar RNA, termed U20.
Alias Symbols: C23
Protein Interaction Partner: HUWE1, PIK3R1, PA2G4, NCL, HNRNPD, AURKA, MDM2, NFE4, CDKN1A, ADAP1, STAU1, ADAP2, UBC, NUP62, ZBTB1, ARFGEF1, RPA3, RPA2, RPA1, ERG, RNF2, SUZ12, EED, EZH2, BMI1, NPM3, EIF3G, XRCC5, PLOD2, NCBP1, MCM2, LMNA, PRMT1, HNRNPK, KCTD12, DNM1, ACLY, SRPK3, TAR
Protein Size: 710

Poids moléculaire: 78 kDa

ID gène: 4691

NCBI Accession: NM_005381, NP_005372

UniProt: P19338

Pathways: Ribonucleoprotein Complex Subunit Organization