Snurportin 1 anticorps (Middle Region)
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- Antigène Voir toutes Snurportin 1 (SNUPN) Anticorps
- Snurportin 1 (SNUPN)
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Épitope
- Middle Region
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Reactivité
- Humain, Souris, Rat, Boeuf (Vache), Cheval, Porc
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Snurportin 1 est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- GVAVPAGPLT TKPDYAGHQL QQIMEHKKSQ KEGMKEKLTH KASENGHYEL
- Homologie
- Cow: 85%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rat: 100%
- Attributs du produit
- This is a rabbit polyclonal antibody against SNUPN. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of human SNUPN
- Top Product
- Discover our top product SNUPN Anticorps primaire
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- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
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Antigen size: 360 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Antigène
- Snurportin 1 (SNUPN)
- Autre désignation
- SNUPN (SNUPN Produits)
- Synonymes
- anticorps rnut1, anticorps zgc:77819, anticorps wu:fc41a03, anticorps SNUPN, anticorps kpnbl, anticorps snurportin1, anticorps KPNBL, anticorps RNUT1, anticorps Snurportin1, anticorps 0610031A09Rik, anticorps Rnut1, anticorps Snupn1, anticorps snurportin 1, anticorps snupn, anticorps SNUPN, anticorps Snupn
- Sujet
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The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. SNUPN interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor.The nuclear import of the spliceosomal snRNPs U1, U2, U4 and U5, is dependent on the presence of a complex nuclear localization signal. The latter is composed of the 5'-2,2,7-terminal trimethylguanosine (m3G) cap structure of the U snRNA and the Sm core domain. The protein encoded by this gene interacts specifically with m3G-cap and functions as an snRNP-specific nuclear import receptor. Alternatively spliced transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: KPNBL, RNUT1, Snurportin1
Protein Interaction Partner: UBC, HOTAIR, MEX3B, XPO1, GCNT3, RNF126, DBN1, RPL17, KPNB1, PAFAH1B2, TNNT3, PEX5, ENO2, RAN, DDX20, ZPR1, SNRPB, SMN1,
Protein Size: 360 - Poids moléculaire
- 41 kDa
- ID gène
- 10073
- NCBI Accession
- NM_005701, NP_005692
- UniProt
- O95149
- Pathways
- Ribonucleoprotein Complex Subunit Organization, Protein targeting to Nucleus
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