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SF3B4 anticorps (N-Term)

SF3B4 Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Saccharomyces cerevisiae, Chévre WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2778952
  • Antigène Voir toutes SF3B4 Anticorps
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Épitope
    • 9
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivité
    • 41
    • 20
    • 19
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Chien, Poisson zèbre (Danio rerio), Lapin, Cobaye, Cheval, Saccharomyces cerevisiae, Chévre
    Hôte
    • 36
    • 5
    • 1
    Lapin
    Clonalité
    • 37
    • 5
    Polyclonal
    Conjugué
    • 25
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SF3B4 est non-conjugé
    Application
    • 35
    • 24
    • 10
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Séquence
    QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT GQHQGYGFVE
    Homologie
    Cow: 100%, Dog: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 86%, Zebrafish: 100%
    Attributs du produit
    This is a rabbit polyclonal antibody against SF3B4. It was validated on Western Blot and immunohistochemistry.
    Purification
    Protein A purified
    Immunogène
    The immunogen is a synthetic peptide directed towards the N terminal region of human SF3B4
    Top Product
    Discover our top product SF3B4 Anticorps primaire
  • Indications d'application
    Optimal working dilutions should be determined experimentally by the investigator.
    Commentaires

    Antigen size: 424 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Antigène
    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
    Autre désignation
    SF3B4 (SF3B4 Produits)
    Synonymes
    anticorps chunp6902, anticorps fb36a04, anticorps wu:fb36a04, anticorps 49kDa, anticorps SF3b49, anticorps SF3b50, anticorps Sap49, anticorps spx, anticorps AFD1, anticorps Hsh49, anticorps SAP49, anticorps Splicing factor 3B subunit 4, anticorps splicing factor 3b, subunit 4, anticorps splicing factor 3b subunit 4 S homeolog, anticorps splicing factor 3b subunit 4, anticorps sap-49, anticorps sf3b4, anticorps Sf3b4, anticorps sf3b4.S, anticorps SF3B4
    Sujet
    SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
    Alias Symbols: Hsh49, SAP49, SF3b49
    Protein Interaction Partner: NCK2, METTL17, ZCCHC10, UBASH3A, NUB1, HSPB7, PPP1R16B, SS18L1, HNRNPUL1, SF3B2, BAIAP2, SEC24D, FAM115A, RBM39, BAG3, CWF19L2, MAPK9, FUS, FRK, FKBP1A, STAU1, UBC, SUMO1, SUZ12, RNF2, PRPF40A, WBP4, APBB1, SRPK3, DDX42, PRPF8, CHERP, DDX17, BCAS2, EFTUD2
    Protein Size: 424
    Poids moléculaire
    47 kDa
    ID gène
    10262
    NCBI Accession
    NM_005850, NP_005841
    UniProt
    Q15427
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