RBM14 anticorps (N-Term)

N° du produit ABIN2778973

Détail du produit anti-RBM14 anticorps

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Cobaye, Boeuf (Vache), Chien, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM14 est non-conjugé

Application: Western Blotting (WB)

Séquence: YAFVHMEKEA DAKAAIAQLN GKEVKGKRIN VELSTKGQKK GPGLAVQSGD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RBM14. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RBM14

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 669 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-RBM14 (ABIN2778973)

Sui, Yang, Xiong, Zhang, Blanchard, Peiper, Dynan, Tuan, Ko: "Gene amplification and associated loss of 5' regulatory sequences of CoAA in human cancers." dans: Oncogene, Vol. 26, Issue 6, pp. 822-35, (2007) (PubMed).

Détails sur RBM14

Antigène: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Autre désignation: RBM14 (RBM14 Produits)

Synonymes: anticorps im:7053198, anticorps wu:fc08a04, anticorps zgc:110682, anticorps sip, anticorps coaa, anticorps psp2, anticorps sytip1, anticorps tmem137, anticorps MGC52864, anticorps MGC132117, anticorps MGC75876, anticorps RBM14, anticorps RBM4, anticorps COAA, anticorps PSP2, anticorps SIP, anticorps SYTIP1, anticorps TMEM137, anticorps 1300007E16Rik, anticorps Sytip, anticorps p16, anticorps p16K, anticorps CoAA, anticorps rbm14, anticorps zgc:85696, anticorps RNA binding motif protein 14a, anticorps RNA binding motif protein 14 L homeolog, anticorps RNA binding motif protein 14, anticorps RNA binding motif protein 14b, anticorps rbm14a, anticorps rbm14.L, anticorps rbm14, anticorps RBM14, anticorps Rbm14, anticorps rbm14b

Sujet: RBM14 contains 2 RRM (RNA recognition motif) domains. Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1.
Alias Symbols: COAA, DKFZp779J0927, SIP, SYTIP1, PSP2, TMEM137
Protein Interaction Partner: UBC, SUMO2, SUMO3, CEP250, DROSHA, MDM2, SMURF2, RPA3, RPA2, RPA1, EZH2, BMI1, RNF2, SUZ12, EED, MAPK15, CDK15, CDK14, HDAC9, HDAC11, WHSC1, VCAM1, TRAF3, ITGA4, FN1, ESR1, ZC3H18, FTSJ3, RBM25, TRMT112, HP1BP3, PRPF19, RBMX, RSL1D1, PRPF6, HNRNPH1, RCC1,
Protein Size: 669

Poids moléculaire: 69 kDa

ID gène: 10432

NCBI Accession: NM_006328, NP_006319

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway