PRPF8 anticorps (N-Term)

N° du produit ABIN2778986

Détail du produit anti-PRPF8 anticorps

Antigène: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Épitope: N-Term

Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Chien, Boeuf (Vache), Cobaye, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRPF8 est non-conjugé

Application: Western Blotting (WB)

Séquence: SHRHSVKSQE PLPDDDEEFE LPEFVEPFLK DTPLYTDNTA NGIALLWAPR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against PRPF8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human PRPF8

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 2335 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PRPF8

Antigène: PRPF8 (PRP8 Pre-mRNA Processing Factor 8 (PRPF8))

Autre désignation: PRPF8 (PRPF8 Produits)

Synonymes: anticorps id:ibd1257, anticorps ik:tdsubc_2a9, anticorps im:7141966, anticorps tdsubc_2a9, anticorps wu:fb37c02, anticorps wu:fb73e06, anticorps xx:tdsubc_2a9, anticorps zgc:56504, anticorps hprp8, anticorps prp-8, anticorps prp8, anticorps prpc8, anticorps rp13, anticorps HPRP8, anticorps PRP8, anticorps PRPC8, anticorps RP13, anticorps SNRNP220, anticorps AU019467, anticorps D11Bwg0410e, anticorps DBF3/PRP8, anticorps Prp8, anticorps Sfprp8l, anticorps pre-mRNA processing factor 8, anticorps pre-mRNA processing factor 8 S homeolog, anticorps Prpf8, anticorps prpf8, anticorps prpf8.S, anticorps PRPF8

Sujet: Pre-mRNA splicing occurs in 2 sequential transesterification steps. PRPF8 is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. The gene encoding PRPF8 is a candidate gene for autosomal dominant retinitis pigmentosa.Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HPRP8, PRP8, PRPC8, RP13
Protein Interaction Partner: SNRNP200, PRPF8, EFTUD2, UBC, CDKN1A, SUMO2, SUMO3, STAU1, LGR4, NEDD8, ERG, ASB15, WWOX, RPA3, RPA2, RPA1, EED, RNF2, SUZ12, rev, PIN1, NEDD4, FBXO6, PRPF4B, UBD, IGSF8, ICAM1, SND1, SF3B2, SLU7, ZNF830, WDR83, PRPF19, GPKOW, FN1, BCAS2, SF3B4, RBM5, VCA
Protein Size: 2335

Poids moléculaire: 273 kDa

ID gène: 10594

NCBI Accession: NM_006445, NP_006436

UniProt: Q6P2Q9