CELF2 anticorps (N-Term)

N° du produit ABIN2779001

Cité dans 1 publication. Cet anticorps anti-CELF2 Polyclonal Lapin (ABIN2779001) détecte spécifiquement CELF2 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Boeuf (Vache).

Aperçu rapide pour CELF2 anticorps (N-Term) (ABIN2779001)

Antigène: CELF2 (CUGBP, Elav-Like Family Member 2 (CELF2))

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CELF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-CELF2 anticorps

Épitope: N-Term

Séquence: TSAFKLDFLP DMMVEGRLLV PDRINGTANK MNGALDHSDQ PDPDAIKMFV

Homologie: Cow: 100%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against CUGBP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human CUGBP2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 521 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-CELF2 (ABIN2779001)

Subramaniam, Natarajan, Ramalingam, Ramachandran, May, Queimado, Houchen, Anant: "Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 294, Issue 4, pp. G1025-32, (2008) (PubMed).

Détails sur CELF2

Antigène: CELF2 (CUGBP, Elav-Like Family Member 2 (CELF2))

Autre désignation: CUGBP2

Sujet: CUGBP2 is a member of the CELF/BRUNOL protein family, which contains two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of CUGBP2 family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. If alternative splicing were to result, multiple transcript variants encoding different isoforms would appear.Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: BRUNOL3, ETR-3, NAPOR, ETR3, CUGBP2
Protein Interaction Partner: PTGS2, ELAVL1, UBC, FN1, APP, PCBP1, A1CF, APOBEC1, Apob,
Protein Size: 521

Poids moléculaire: 56 kDa

ID gène: 10659

NCBI Accession: NM_006561, NP_006552

Pathways: Ribonucleoprotein Complex Subunit Organization