RBMXL2 anticorps (Middle Region)

N° du produit ABIN2779064

Détail du produit anti-RBMXL2 anticorps

Antigène: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Épitope: Middle Region

Reactivité: Humain, Souris, Lapin, Rat, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBMXL2 est non-conjugé

Application: Western Blotting (WB)

Séquence: SSRDGYSSRD YREPRGFAPS PGEYTHRDYG HSSVRDDCPL RGYSDRDGYG

Homologie: Cow: 85%, Dog: 77%, Guinea Pig: 77%, Horse: 77%, Human: 100%, Mouse: 77%, Rabbit: 85%, Rat: 85%

Attributs du produit: This is a rabbit polyclonal antibody against RBMXL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human RBMXL2

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 392 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RBMXL2

Antigène: RBMXL2 (RNA Binding Motif Protein, X-Linked-Like 2 (RBMXL2))

Autre désignation: RBMXL2 (RBMXL2 Produits)

Synonymes: anticorps HNRNPG-T, anticorps HNRNPGT, anticorps HNRPGT, anticorps 1700012H05Rik, anticorps Hnrnpg-t, anticorps RBMX, anticorps hnRNP G-T, anticorps RNA binding motif protein, X-linked like 2, anticorps RNA binding motif protein, X-linked-like 2, anticorps RBMXL2, anticorps Rbmxl2

Sujet: The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. RBMXL2 has two RRM domains that bind RNAs. RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
Alias Symbols: HNRNPG-T, HNRPGT, HNRNPGT
Protein Interaction Partner: UBC, RABGGTA, FDXACB1, CAND1, COPS5, CUL1, CUL3, CUL4B, SUMO1, DYRK2, TRA2B,
Protein Size: 392

Poids moléculaire: 43 kDa

ID gène: 27288

NCBI Accession: NM_014469, NP_055284

UniProt: O75526